牛蒡子苷结构式
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常用名 | 牛蒡子苷 | 英文名 | Arctiin |
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CAS号 | 20362-31-6 | 分子量 | 534.552 | |
密度 | 1.4±0.1 g/cm3 | 沸点 | 756.4±60.0 °C at 760 mmHg | |
分子式 | C27H34O11 | 熔点 | 109 °C | |
MSDS | 中文版 美版 | 闪点 | 250.1±26.4 °C |
牛蒡子苷用途Arctiin(NSC 315527)是植物木酚素,可从牛蒡种子中提取,具有抗癌活性。 |
中文名 | 牛蒡子苷 |
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英文名 | Arctiin |
中文别名 | 牛蒡苷 |
英文别名 | 更多 |
描述 | Arctiin(NSC 315527)是植物木酚素,可从牛蒡种子中提取,具有抗癌活性。 |
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相关类别 | |
参考文献 |
[1]. Huang DM, et al. Modulation of anti-adhesion molecule MUC-1 is associated with arctiin-induced growth inhibition in PC-3 cells. Prostate. 2004 May 15;59(3):260-7. [2]. Knipping K, et al. In vitro and in vivo anti-allergic effects of Arctium lappa L. Exp Biol Med (Maywood). 2008 Nov;233(11):1469-77. [3]. Zeng Y, et al. Lack of significant modifying effect of arctiin on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats. Cancer Lett. 2005 May 26;222(2):145-51. [4]. Wu JG, et al. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats. Phytomedicine. 2009 Nov;16(11):1033-41. [5]. Ma ST, et al. Effect of arctiin on glomerular filtration barrier damage in STZ-induced diabetic nephropathy rats. Phytother Res. 2013 Oct;27(10):1474-80. [6]. Matsuzaki Y, et al. Arctiin induces cell growth inhibition through the down-regulation of cyclin D1 expression. Oncol Rep. 2008 Mar;19(3):721-7. |
密度 | 1.4±0.1 g/cm3 |
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沸点 | 756.4±60.0 °C at 760 mmHg |
熔点 | 109 °C |
分子式 | C27H34O11 |
分子量 | 534.552 |
闪点 | 250.1±26.4 °C |
精确质量 | 534.210083 |
PSA | 153.37000 |
LogP | 0.23 |
外观性状 | 白色至灰白色固体 |
蒸汽压 | 0.0±2.7 mmHg at 25°C |
折射率 | 1.601 |
储存条件 | ?20°C |
危险品运输编码 | NONH for all modes of transport |
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Plasma pharmacokinetics and tissue distribution of arctiin and its main metabolite in rats by HPLC-UV and LC-MS.
Planta Med. 78(8) , 800-6, (2012) The pharmacokinetic profile of arctiin, the major active lignan in fruits of Arctium lappa L., was investigated. Its main meta"bolite arctigenin was identified by an LC-MS method, and an HPLC-UV techn... |
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Simultaneous determination of arctiin and its metabolites in rat urine and feces by HPLC.
Fitoterapia 86 , 6-12, (2013) Arctiin, an important lignan compound in Fructus Arctii, has been reported to possess various kinds of bioactivities. Previous studies on the pharmacokinetic of arctiin after oral administration showe... |
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Effects of arctiin on streptozotocin-induced diabetic retinopathy in Sprague-Dawley rats.
Planta Med. 78(12) , 1317-23, (2012) Diabetic retinopathy is one of the most common and severe complications of diabetes mellitus. Arctiin, a bioactive compound isolated from the dry seeds of Arctium lappa L., has been reported to have a... |
MFCD00870630 |
Arctiin (8CI) |
4-{[(3R,4R)-4-(3,4-Dimethoxybenzyl)-2-oxotetrahydro-3-furanyl]methyl}-2-methoxyphenyl β-D-glucopyranoside |
Arctigenin-4-glucoside |
Arctin |
Arctlin |
2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(b-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-, (3R,4R)- |
Arctiin |
4-{[(3R,4R)-4-(3,4-Dimethoxybenzyl)-2-oxotetrahydrofuran-3-yl]methyl}-2-methoxyphenyl β-D-glucopyranoside |
2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl)methyl]-3-[[4-(β-D-glucopyranosyloxy)-3-methoxyphenyl]methyl]dihydro-, (3R,4R)- |
Great Burdock Root Extract |
NSC 315527 |
Acrctiin |