化源商城直购
中文名 | 二硫代苏糖醇 |
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英文名 | DL-Dithiothreitol |
中文别名 |
1,4-二硫代苏糖醇
二硫苏糖醇 DL-1,4-二硫苏糖醇 1,4-二硫-DL-苏糖醇 (+/-)-二硫苏糖醇 1,4二巯基苏糖醇DTT DL-二硫苏糖醇 |
英文别名 |
DITHIOERYTHRITOL
DTT 1,4-Dithiothreitol L-(−)-Dithiothreitol 1,4-Bissulfanylbutane-2,3-diol DL-1,4-Dimercapto-2,3-dihydroxybutane 2,3-Butanediol, 1,4-dimercapto-, (2S,3S)- THREO-2,3-DIHYDROXY-1,4-DITHIOLBUTANE (2R,3R)-(-)-2,3-Dihydroxy-1,4-butanedithiol 1,4-Disulfanyl-2,3-butanediol Threitol, 1,4-dithio- (R*,R*)-1,4-DIMERCAPTO-2,3-BUTANEDIOL EINECS 222-468-7 L-Dithiothreitol (2S,3S)-1,4-Disulfanyl-2,3-butanediol Cleland's Reagent (2S,3S)-1,4-Disulfanylbutane-2,3-diol (2R*,3S*)-1,4-dimercaptobutane-2,3-diol dithiothreitol threo-2,3-Dihydroxy-1,4-butanedithiol (2R*,3S*)-1,4-dimercapto-2,3-butanediol Sputolysin (2R,3R)-(-)-1,4-Dimercapto-2,3-butanediol L-Cleland's 1,4-Disulfanylbutane-2,3-diol 2,3-Butanediol, 1,4-dimercapto- MFCD00004877 (±)-1,4-Dimercapto-2,3-butanediol |
密度 | 1.3±0.1 g/cm3 |
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沸点 | 364.5±42.0 °C at 760 mmHg |
熔点 | 41-44?°C(lit.) |
分子式 | C4H10O2S2 |
分子量 | 154.251 |
闪点 | 174.2±27.9 °C |
精确质量 | 154.012222 |
PSA | 118.06000 |
LogP | 0.07 |
外观性状 | 白色粉末 |
蒸汽压 | 0.0±1.8 mmHg at 25°C |
折射率 | 1.579 |
储存条件 | 2-8℃ |
稳定性 | 常温常压下稳定 |
水溶解性 | Soluble |
分子结构 | 1、 摩尔折射率:39.36 2、 摩尔体积(m3/mol):118.4 3、 等张比容(90.2K):323.2 4、 表面张力(dyne/cm):55.5 5、 极化率(10 -24cm 3):15.60 |
计算化学 | 1、 疏水参数计算参考值(XlogP):-0.4 2、 氢键供体数量:2 3、 氢键受体数量:2 4、 可旋转化学键数量:3 5、 拓扑分子极性表面积(TPSA):40.5 6、 重原子数:8 7、 表面电荷:0 8、 复杂度:52 9、 同位素原子数量:0 10、 确定原子立构中心数量:2 11、 不确定原子立构中心数量:0 12、 确定化学键立构中心数量:0 13、 不确定化学键立构中心数量:0 14、 共价键单元数量:1 |
更多 | 1. 性状:未确定 2. 密度(g/mL,25/4℃):1.04 3. 相对蒸汽密度(g/mL,空气=1):未确定 4. 熔点(ºC):41-44 5. 沸点(ºC,2mmhg):125-130 6. 沸点(ºC,5.2kPa):未确定 7. 折射率:未确定 8. 闪点(ºF):>230 9. 比旋光度(º):未确定 10. 自燃点或引燃温度(ºC):未确定 11. 蒸气压(kpa,20ºC):未确定 12. 饱和蒸气压(kPa,60ºC):未确定 13. 燃烧热(KJ/mol):未确定 14. 临界温度(ºC):未确定 15. 临界压力(KPa):未确定 16. 油水(辛醇/水)分配系数的对数值:未确定 17. 爆炸上限(%,V/V):未确定 18. 爆炸下限(%,V/V):未确定 19. 溶解性:未确定 |
Synonym:Cleland's Reagent; Threo-1,4-Dimercapto-2,3-Butanediol; DTT Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW
The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Dusts may be combustible when exposed to heat, flame, or oxidizing agents. Runoff from fire control or dilution water may cause pollution. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Use agent most appropriate to extinguish fire. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Keep refrigerated. (Store below 4C/39F.) Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 27565-41-9: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to minimize contact with skin. Respirators: Wear a NIOSH/MSHA or European Standard EN 149 approved full-facepiece airline respirator in the positive pressure mode with emergency escape provisions. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Powder Color: white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 42.00 - 44. Autoignition Temperature: Not available. Flash Point: > 110 deg C (> 230.00 deg F) Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: freely soluble in ethanol, acetone, ethe Specific Gravity/Density: Molecular Formula: HSCH2CH(OH)CH(OH)CH2SH Molecular Weight: 154.24 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable at room temperature in closed containers under normal storage and handling conditions. Conditions to Avoid: Incompatible materials, dust generation, excess heat. Incompatibilities with Other Materials: Alkali metals, bases, reducing agents, oxidizing agents. Hazardous Decomposition Products: Carbon monoxide, oxides of sulfur, carbon dioxide, hydrogen sulfide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 27565-41-9: XO8576500 LD50/LC50: Not available. Carcinogenicity: DL-Dithiothreitol, DNase, RNase, Protease Free - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 27565-41-9: No information available. Canada CAS# 27565-41-9 is listed on Canada's DSL List. CAS# 27565-41-9 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 27565-41-9 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A |
毒理学数据: 1、急性毒性: 小鼠腹腔LD50:169mg/kg;小鼠皮下LD50:333mg/kg; 小鼠静脉LD50:94 mg/kg; 2、致突变:沙门氏菌:100ug/plate cc彩球网:CHEMICAL IDENTIFICATION
cc彩球网:HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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:β (欧洲) | Xn |
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风险声明 (欧洲) | 25-36/37/38-22-20/21/22 |
安全声明 (欧洲) | S26-S45 |
WGK德国 | 3 |
RTECS号 | EK1610000 |
海关编码 | 2930909090 |
上游产品 0 | |
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下游产品 4 | |
海关编码 | 2930909090 |
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中文概述 | 2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0% |
申报要素 | 品名, 成分含量, 用途 |
Summary | 2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |